LD Collins

L.D. Collins and Co. Ltd
Company Reg No: 987004

Cyclogest - Areas of Use

Assisted Reproductive Technology

Infertility is when a couple cannot get pregnant (conceive), despite having regular unprotected sex.

Around one in seven couples may have difficulty conceiving. This is approximately 3.5 million people in the UK.

A couple will only be diagnosed as being infertile if they have not managed to have a baby after one year of trying.

Assisted Reproductive Technology (ART) is the technology used to achieve pregnancy in procedures such as artificial insemination and in-vitro fertilization (IVF) and is also known as fertility treatment.

After ovulation, during the latter half of the menstrual cycle, the body releases progesterone. This hormone helps to sustain a pregnancy after the egg is fertilized. Progesterone prepares the lining of the uterus (endometrium) to allow a fertilized egg (embryo) to stick or implant.

Many scientific studies have looked at pregnancy rates in IVF cycles that used supplemental progesterone. These studies have shown that pregnancy rates are much higher compared to cycles where no progesterone was used.

CYCLOGEST is indicated for women who need extra progesterone while undergoing treatment in an Assisted Reproductive Technology (ART) programme.

(Ref: http://www.nhs.uk/conditions/Infertility/Pages/Introduction.aspx)

Post-Natal Depression

Postpartum depression (PPD), also called postnatal depression (PND), is a form of clinical depression which can affect women, and less frequently men, after childbirth.

PND occurs in women after they have carried a child, usually in the first few months. Symptoms of postnatal depression are broad, and can include a low mood, sleeping difficulties and a general sense of feeling unable to cope.

About 1 in 10 mothers develop PND. Support and understanding from family, friends, and sometimes from a professional such as a health visitor can help you to recover. Other treatment options include antidepressant drugs and psychological treatments such as cognitive behaviour therapy.

(Ref: http://www.nhs.uk/Conditions/Postnataldepression/Pages/Introduction.aspx)


Symptoms of PND can occur anytime in the first year postpartum and include, but are not limited to, the following:

  • Low mood
  • Loss of interest in interaction and reduced ability to take pleasure in things that you used to enjoy
  • Lack of energy
  • Sleeping difficulties
  • Difficulties with cocentration and decision-making
  • Low self-esteem
  • Decreased appetite or an increase in appetite
  • Feelings of agitation or apathy
  • Feelings of guilt and self-blame
  • Thoughts of suicide and self-harm

(Ref: http://www.nhs.uk/Conditions/Postnataldepression/Pages/Symptoms.aspx)

Pre-Menstrual Syndrome

Premenstrual syndrome (PMS) (also called PMT or premenstrual tension) is a collection of physical, psychological, and emotional symptoms related to a woman's menstrual cycle. Most women of child-bearing age report having experienced symptoms related to PMS (1 in 20 experience more severe symptoms which prevent them living their normal lives, normally a result of a more intense variation of PMS known as premenstrual dysphoric disorder). PMS symptoms are usually predictable and occur regularly during the ten days prior to menses, tending to improve aropund the time of the start of menstrual flow.

(Ref: http://www.nhs.uk/Conditions/Premenstrual-syndrome/Pages/Introduction.aspx)


More than 100 different symptoms have been associated with PMS; some of the most prominent physical ones are:

  • Headaches
  • Pain and discomfort in the abdomen
  • Feeling bloated

Common emotional symptoms include:

  • Mood swings
  • High enotion
  • Anxiety

The exact symptoms and their intensity vary from woman to woman and even from cycle to cycle. Most women with premenstrual syndrome experience only a few of the possible symptoms, in a relatively predictable pattern.

(Ref: http://www.nhs.uk/Conditions/Premenstrual-syndrome/Pages/Symptoms.aspx)


Laurence Collins was born Aug 21 1931 in Stamford Hill, London. His family moved to Cockfosters, Barnet in 1937. Laurence studied at Bedford School until 1949, gaining School Certificate aged 16 and Higher School Certificate in Physics, Chemistry, Biology....

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